Gastric acid induces mucosal H2S release in rats by upregulating mRNA and protein expression of cystathionine gamma lyase

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Duodenal acidification stimulates gastric H2S release through upregulating mRNA expression of cystathionine gamma lyase

Introduction: It has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of H2S, but till now the effect of duodenal acidification on gastric H2S release has not been investigated. Therefore, the present study designed to evaluate the effects of duodenal acidification on gastric H2S release and level of mRNA expression of cys...

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duodenal acidification stimulates gastric h2s release through upregulating mrna expression of cystathionine gamma lyase

introduction: it has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of h2s, but till now the effect of duodenal acidification on gastric h2s release has not been investigated. therefore, the present study designed to evaluate the effects of duodenal acidification on gastric h2s release and level of mrna expression of cystath...

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Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

Objective(s): This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase (CBS), and mucosal release of H2S in gastric mucosa in rats. Materials and Methods:Thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, HCl (10 mM) treated g...

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mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

objective(s): this study was performed to investigate the effects of mucosal acidification on mrna expression and protein synthesis of cystathionine gamma lyase (cse), cystathionine beta synthase (cbs), and mucosal release of h2s in gastric mucosa in rats. materials and methods:thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, hcl (10 mm) treated gr...

متن کامل

Mucosal acidification increases hydrogen sulfide release through up-regulating gene and protein expressions of cystathionine gamma-lyase in the rat gastric mucosa

OBJECTIVES This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase (CBS), and mucosal release of H2S in gastric mucosa in rats. MATERIALS AND METHODS Thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, HCl (10 mM) treated gro...

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ژورنال

عنوان ژورنال: The Journal of Physiological Sciences

سال: 2015

ISSN: 1880-6546,1880-6562

DOI: 10.1007/s12576-015-0392-5